Trace Elements in Medicine (Moscow)
2019, 20(3): 45-53
ORIGINAL PAPERS

THE HUMAN SELENIUM STATUS OF KHABAROVSK LAND IN 2018

J.G. Kovalsky¹, N.A. Golubkina², T.T. Papazyan³, O.A. Senkevich¹

¹ Far-Eastern State Medical University, ul. Muravyev-Amursky, 35, Khabarovsk, 68000, Russia
² Federal Scientific Center of Vegetable Production, Moscow Region 143072, Alltechcorp, Moscow, 105005, Russia
³ «Alltech» LLC, emb. Academician Tupolev, 15 k.2, Moscow, 10500, Russia

DOI: 10.19112/2413-6174-2019-20-3-45-53 

ABSTRACT. Human selenium status optimisation is considered to be one of the key elements of increasing longevity, decreasing mortality levels from cardiovascular diseases and cancer. During the period of wheat import from endemic region of the world characterized by high selenium level most territory of Russia was characterized by moderate selenium deficiency. The aim of the present work was evaluation of the human selenium status in Khabarovsk land in 2018 after the beginning of exclusive utilization of domestic grain. It was shown that compared to the 2008 data serum selenium levels decreased 1.6 times in Khabarovsk, 1.4 times- in Okhotsk and 1.1 times in Komsomolsk-na-Amure (Mean serum Se levels 51.5±6.8, 62.1±8.9 and 60.9±6.5 µg/L accordingly).Excess of maximum permissible concentration levels of selenium antagonist- cadmium reached 6.6. 2.7 timesand 1.7 accordingly TheresultindicatethatatpresentKhabarovsklandischaracterizedbysevere selenium deficiency comparable with that registered in Finland in 1980 before the beginning of selenium fertilizers utilization. Among possible ways of selenium consumption levels optimization (utilization of Se-premixes, agrochemical biofortification of plants, agricultural crops selection and increase of soil Se bioavailability, new natural Se accumulators utilization, Se-enriched plants with pronounced anticancer activity) the most efficient one seems to be utilization of Se- premixes due to the existence of industrial production and availability of the resulting products (eggs and other poultry products) to all segments of population.

KEYWORDS: selenium deficiency, Khabarovsk land, methods of selenium status optimization.